Malaria can damage the kidneys or liver or cause the spleen to rupture. Any of these conditions can be life-threatening. Anemia. Malaria may result in not having enough red blood cells for an adequate supply of oxygen to your body's tissues (anemia).In humans, the parasites grow and multiply first in the liver cells and then in the red cells of the blood. In the blood, successive broods of parasites grow inside the red cells and destroy them, releasing daughter parasites (“merozoites”) that continue the cycle by invading other red cells.More organ-specific findings include fatty infiltration of the liver, hyaline membrane formation in the lungs, fatty degeneration of myofibrils and brown atrophy in the heart and “Durck” granuloma in the brain.
What damage does malaria inflict : Anemia (loss of oxygen in the blood) and jaundice (yellow coloring of the skin and eyes) because of the loss of red blood cells. If not treated right away, the infection can become serious. It may cause kidney failure, seizures, mental confusion, coma, and death.
Does malaria damage the spleen
The spleen is a complex organ that is perfectly adapted to selectively filtering and destroying senescent red blood cells (RBCs), infectious microorganisms and Plasmodium-parasitized RBCs. Infection by malaria is the most common cause of spleen rupture and splenomegaly, albeit variably, a landmark of malaria infection.
What does malaria do to the liver : Hepatic dysfunction and jaundice are common features of severe malaria [[6], [7], [8], [9]]. Histopathological changes in the liver range from hepatocyte necrosis, granulomatous lesions, Kupffer cell hyperplasia, malarial pigmentation, cholestasis, monocyte infiltrations to malarial nodules [7,10,11].
Malaria parasites go through a series of steps on their way to causing disease in humans. When a malaria-carrying mosquito bites a human host, the malaria parasite enters the bloodstream, multiplies in the liver cells, and is then released back into the bloodstream, where it infects and destroys red blood cells.
Malaria is caused by the parasites, not by a virus or by a type of bacterium. If it isn't treated, malaria can cause severe health problems such as seizures, brain damage, trouble breathing, organ failure and death.
How does malaria affect the liver
Hepatic dysfunction and jaundice are common features of severe malaria [[6], [7], [8], [9]]. Histopathological changes in the liver range from hepatocyte necrosis, granulomatous lesions, Kupffer cell hyperplasia, malarial pigmentation, cholestasis, monocyte infiltrations to malarial nodules [7,10,11].The human malaria blood stage can impair not only the establishment of an adequate immune response, but also previously acquired responses.Neurologic defects may occasionally persist following cerebral malaria, especially in children. Such defects include trouble with movements (ataxia), palsies, speech difficulties, deafness, and blindness.
The spleen is a complex organ that is perfectly adapted to selectively filtering and destroying senescent red blood cells (RBCs), infectious microorganisms and Plasmodium-parasitized RBCs. Infection by malaria is the most common cause of spleen rupture and splenomegaly, albeit variably, a landmark of malaria infection.
Does malaria destroy liver cells : Liver injury is a known feature of severe malaria, but is only incidentally investigated in uncomplicated disease. In such cases, drug-induced hepatotoxicity is often thought to be the primary cause of the observed liver injury, and this can be a major concern in antimalaria drug development.
Can malaria damage the kidneys : Kidney complications in malaria mainly occur due to hemodynamic dysfunction and immune response. Liver complications leading to hepatomegaly, jaundice and hepatic dysfunction can also contribute to the occurrence of acute kidney injury.
Which organ is most affected by malaria spleen
The spleen is a complex organ that is perfectly adapted to selectively filtering and destroying senescent red blood cells (RBCs), infectious microorganisms and Plasmodium-parasitized RBCs. Infection by malaria is the most common cause of spleen rupture and splenomegaly, albeit variably, a landmark of malaria infection.
If malaria is diagnosed and treated quickly, you should fully recover. Treatment should be started as soon as possible. Treatment begins in a hospital to make sure complications don't suddenly develop. Treatment is with tablets or capsules.Although it is well known that malaria episodes due to P. malariae can occur even after 30–50 years following a previous malaria attack, the mechanism responsible for its persistence and late recurrence still remains a medical mystery [5,6,7,8].
Can malaria damage the liver : The World Health Organization (WHO) guidelines reports that severe malaria can cause multi-organ failure and liver damage, with jaundice being relatively common [16].